Final answer:
A working application after a clean boot suggests software conflicts in normal operation, likely with startup programs or services. Troubleshooting involves systematically re-enabling these items to find and fix the conflict.
Step-by-step explanation:
If an application works after a clean boot but does not work when Windows is loaded normally, you can assume that there are external factors affecting the application's performance in the normal boot scenario. This often points to a conflict with either startup programs or services that load automatically when Windows starts regularly.
In a clean boot state, Windows is started with a minimal set of drivers and startup programs. This can help you rule out software conflicts that occur when running the application under normal operation conditions. The assumption here is that the problematic factor is not part of the boot process in the clean boot scenario.
To troubleshoot further, you would systematically enable services and startup programs to identify the culprit. Once you've identified the interfering program or service, you can take steps to resolve the conflict, such as updating, reconfiguring, disabling, or uninstalling the problematic software.