Final answer:
Large areas of east Africa are devoid of cattle due to the introduction of cattle diseases such as rinderpest by colonizers, leading to the spread of tsetse flies and sleeping sickness.
Step-by-step explanation:
The large areas of east Africa are devoid of cattle today primarily because colonizers introduced cattle diseases to the region, most notably rinderpest. This disease, brought to the Horn of Africa by Italians, quickly spread through herds across eastern and southern Africa, heavily impacting livestock populations. The environmental change, with diminished herds leading to the flourishing of thornbush shrubs, created an ideal habit for the tsetse flies, which transmit sleeping sickness both to humans and animals. This shows the extensive and long-term ecological disruptions caused by colonial practices and the introduction of non-native diseases to the region.