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What is the best method of dosing if you have two very different athletes with the same long term training goals, one with 50 kgs of lean mass and one with 100 kgs of lean mass? NOTE: these athletes are not looking for rapid gains.

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Final answer:

Individualized dosing that considers each athlete's unique physiology, such as lean body mass and metabolic rate, is necessary for minimizing side effects and achieving training goals. Standard doses typically given to adults regardless of mass may require adjustment for those with significantly different lean body masses.

Step-by-step explanation:

The best method of dosing for two athletes with different amounts of lean mass but the same long-term training goals should take into account individual factors such as their lean body mass, metabolic rate, and potential for side effects. In general, dosages may need to be tailored to each individual to minimize the risk of side effects while achieving the desired therapeutic effect. For athletes with different lean masses (e.g., 50 kg vs. 100 kg), dosing purely based on mass might not be appropriate for adults as it is for children, since typically a single standard dose is used regardless of an adult's mass. However, considering the distinct difference in lean mass between the two athletes, adjustments may be warranted. It's also important to monitor their responses to the dosing regimen since factors like drug metabolism and possible liver or kidney dysfunctions might affect drug clearance, leading to toxicity or enhanced side effects.

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