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In order to test the effectiveness of a new drug in reducing cholesterol level, a random sample of 45 patients who have a higher than normal cholesterol level was chosen. The cholesterol level of each of the patients was measured and recorded before and then after taking the new drug for a period of 6 weeks, and the differences (before − after) were calculated.

In this case, which of the following is the appropriate set of hypotheses?

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None of the above. This is not a matched pairs situation.

How to determine the appropriate set of hypotheses

When we perform a matched pairs t-test, we assume that the differences between the before and after measurements are normally distributed.

However, the test p-value is less than 0.05, which means that we can reject the null hypothesis that the data is normally distributed.

So, we cannot use a matched pairs t-test.

Since the data is not normally distributed, we should use a non-parametric test.

Missing information in the question

In order to test the effectiveness of a new drug in reducing cholesterol level, a random sample of 45 patients who have a higher than normal cholesterol level was chosen. The cholesterol level of each of the patients was measured and recorded before and then after taking the new drug for a period of 6 weeks, and the differences (before − after) were calculated.

In this case, which is the appropriate set of hypotheses?

(H o: μd = 0) and (Ha: μd < 0)

(H o: μd = 0) and (Ha: μd > 0)

(H o: μd = 0) and (Ha: μd ≠ 0)

None of the above. This is not a matched pairs situation.

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