Final answer:
Historical interpretation shows that the acquisition of land was a significant factor in early U.S. Indian policy, often leading to the displacement of Native American tribes. Thus, the statement can be considered true in a broad historical context.
Step-by-step explanation:
The question of whether the acquisition of land was the most important motivating factor in the formulation of early U.S. Indian policy is a matter of historical interpretation. While land acquisition was indeed a significant motivating factor, early U.S. Indian policy was also influenced by various other considerations such as trade, security, and diplomatic relations with Native American tribes. It is important to analyze the context and differing perspectives when answering this question.
Historically, the desire for land expansion and control of territory was a powerful driver in the formulation of policies related to Native Americans. This often resulted in the displacement and unfair treatment of Native peoples during the early years of the United States. Therefore, it can be argued that the statement is true, acknowledging that this is a simplified overview of a complex historical issue.