Final answer:
Clinical infection of candidiasis can occur due to disruptions in normal flora, immunosuppression, and changes in the body's environment. It is diagnosed via microscopic evaluation, clinical observation, and specialized tests.
Step-by-step explanation:
Three factors that determine if clinical infection of candidiasis occurs include:
- Disruptions in normal flora: The use of antibiotic therapy, which can kill off bacteria that normally inhibit the growth of Candida, allowing it to overgrow.
- Immunosuppression: Conditions such as HIV, AIDS, cancer, or the use of immunosuppressant drugs can allow Candida to thrive due to the weakened immune system.
- Changes in body environment: Factors like untreated diabetes can result in favorable conditions for Candida growth, such as high glucose levels in saliva (causing oral thrush) or changes in vaginal pH due to decreased estrogen (leading to vaginal yeast infections).
Candidiasis is typically diagnosed through microscopic evaluation of secretions, clinical observations, and specialized tests, such as the presence of germ tubes or molecular tests.