Final answer:
An elevated serum creatinine level of 3.0 mg/dL in a post-kidney transplant patient is a potential indication of kidney rejection. Such an increase requires immediate medical attention and further diagnostic testing to determine the appropriate course of action.
Step-by-step explanation:
A serum creatinine level of 3.0 mg/dL is an indication that the adolescent may be rejecting the kidney. Normal serum creatinine levels are usually between 0.8-1.2 mg/dL for males and 0.6-0.9 mg/dL for females. In the context of kidney transplantation, a serum creatinine level that is three times the baseline or a urine output below 0.3 ml/kg for 24 hours is cause for concern and may indicate acute renal failure (ARF) or transplant rejection. It is important to monitor patients closely for signs of rejection or kidney function deterioration after a transplant.
Symptoms such as increased fatigue, changes in urine output, and significant changes in laboratory values like serum creatinine highlight the importance of immediate medical intervention to preserve the function of the transplanted kidney. A biopsy and other diagnostic tests may be necessary to confirm rejection and guide treatment.