Final answer:
The main organ that is the main route of elimination is the kidneys. Other organs involved in excretion include the large intestine, liver, skin, and lungs. The kidneys filter substances out of the blood and produce urine.
Step-by-step explanation:
The main organ that is the main route of elimination is the kidneys. They play a crucial role in removing waste products and excess water from the bloodstream by producing urine. The kidneys filter substances out of the blood, reabsorb needed materials, and use the remaining waste products to form urine.
Other organs involved in excretion include the large intestine, liver, skin, and lungs. The large intestine eliminates solid waste after food digestion and water extraction. The liver breaks down toxins and excretes waste products in bile. The skin eliminates water, salts, and a small amount of urea through sweat. The lungs excrete carbon dioxide and other waste gases through exhaled air.