Question

Pregnancy is a hypercoagulable state in which women are at a fivefold to sixfold increased risk for thromboembolic disease. The tendency for blood to clot is greater, attributable to an increase in various clotting factors. Which of these come into play during pregnancy?

1) Factor VII
2) Factor VIII
3) Factor IX
4) Factor XIII
5) Fibrinogen

Answer 1

During pregnancy, the risk of thromboembolic disease increases due to higher levels of clotting factors including Factor VII, Factor VIII, Factor IX, Factor X, Factor XII, Factor XIII, and Fibrinogen (Factor I), produced by the liver.

Step-by-step explanation:

During pregnancy, the body becomes a hypercoagulable state, increasing the risk of thromboembolic disease significantly. This is due to an increase in various clotting factors to prevent excessive bleeding during childbirth. Specifically, the clotting factors that come into play during pregnancy include Factor VII, Factor VIII, Factor IX, Factor X, Factor XII, Factor XIII, and Fibrinogen (Factor I), all of which are essential for the coagulation process. These factors are produced by the liver and play vital roles in the body's ability to form clots. The liver's increased production of these factors during pregnancy is one of several physiological adaptations that occur to protect both the mother and the developing fetus.