Final answer:
True, variable-oriented research aligns with the nomothetic model as both seek generalizable patterns. Useful data include results that do not support hypotheses, and experimentation is not the sole scientific investigation method. Larger sample sizes in experiments are preferable for reliability.
Step-by-step explanation:
Variable-oriented research is indeed similar to the nomothetic model of explanation, making the answer to the question True. The nomothetic model seeks to explain phenomena based on general laws and patterns that apply widely across multiple cases. Similarly, variable-oriented research focuses on identifying and understanding how different variables relate to one another across a large number of cases.
Data that does not support a hypothesis can still be useful because it contributes to the scientific understanding by ruling out certain explanations or leading to further inquiry, thus the statement that it is not useful is False. In the context of scientific investigations, experimentation is very important, but it is not the only valid type of scientific investigation, as observational and correlational studies also contribute valuable knowledge to the field, making the statement False.
Concerning the conduction of experiments on humans, it is not true that experiments cannot be done on humans. There are strict ethical guidelines and regulatory frameworks in place to ensure the safety and consent of human participants, so the statement is False. It is generally true that larger sample sizes are better than smaller ones in scientific experiments because they provide more reliable data and a better representation of the general population, making the statement True.