Question

A nurse is reviewing the laboratory results of a client undergoing screening for primary cushing's disease. The nurse should expect an elevation in which of the following laboratory findings?

A. Lymphocyte count
B. potassium
C. calcium
D. glucose

Answer 1

The nurse should expect an elevation in glucose levels. Therefore, the correct option is D. glucose.

Step-by-step explanation:

Cushing's disease, characterized by excessive cortisol production, leads to increased glucose production in the liver (gluconeogenesis) and decreased glucose utilization by peripheral tissues. Consequently, elevated blood glucose levels occur. Cortisol also promotes insulin resistance, further contributing to hyperglycemia. Therefore, during screening for primary Cushing's disease, an elevation in glucose levels is a key laboratory finding.

Options A (lymphocyte count), B (potassium), and C (calcium) are not typically associated with primary Cushing's disease. In fact, hypercortisolism can cause lymphopenia, hypokalemia, and hypercalcemia due to its various effects on immune function, electrolyte balance, and bone metabolism.

In summary, the expected elevation in glucose aligns with the pathophysiology of Cushing's disease, making it a crucial parameter to monitor in laboratory results. Therefore, the correct option is D. glucose.

Answer 2

The nurse should expect an elevation in glucose levels in a client undergoing screening for primary Cushing's disease. Therefore, the correct option is D.

Step-by-step explanation:

Primary Cushing's disease is characterized by the overproduction of cortisol, a hormone that plays a crucial role in glucose metabolism. Elevated cortisol levels can lead to increased gluconeogenesis (formation of glucose from non-carbohydrate sources) and insulin resistance, resulting in higher blood glucose levels.

Therefore, during screening for Cushing's disease, an elevation in glucose levels is anticipated due to the dysregulation of cortisol. Monitoring glucose levels is an essential component of the diagnostic process for Cushing's disease.

Lymphocyte count (Option A) is not typically affected in Cushing's disease. Potassium (Option B) and calcium (Option C) levels may be altered due to other factors, such as medications or concurrent medical conditions, but they are not the primary indicators of Cushing's disease.

In summary, an elevation in glucose levels is a key laboratory finding associated with the hypercortisolism characteristic of Cushing's disease and is crucial for the diagnosis and management of this endocrine disorder.

Therefore, the correct option is D.