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The ___________________ of the central nervous system regulate the external environment around the neurons.

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Final answer:

Astrocytes are the central nervous system cells that regulate ions, manage neurotransmitter levels, and help form the blood-brain barrier.

Step-by-step explanation:

The cells of the central nervous system that regulate ions, help in the uptake and/or breakdown of neurotransmitters, and contribute to the formation of the blood-brain barrier are astrocytes. Astrocytes are a type of glial cell that supports and protects neuronal cells. These cells are involved in maintaining the homeostasis of the brain's environment, which is vital for the functioning of neurons. The astrocytes regulate the concentration of ions and neurotransmitters around neurons and play a crucial role in the neurovascular unit that constitutes the blood-brain barrier, a selective barrier that prevents certain substances from the blood from entering the brain tissue.

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