Question

To determine the major E2 elimination product, which Newman projection should be drawn?

a) Newman projection 1
b) Newman projection 2
c) Newman projection 3
d) Newman projection 4

Answer 1

To determine the major E2 elimination product, the Newman projection drawn should show the molecule with the leaving group and the beta hydrogen anti to one another in a staggered conformation.

Step-by-step explanation:

To determine the major E2 elimination product, the correct Newman projection to draw is one that shows the molecule in the conformation that places the leaving group and the beta hydrogen anti to one another. This conformation allows for the most efficient overlap of the orbitals during the elimination process. Generally, this would be a staggered conformation with the leaving group and the beta hydrogen 180 degrees apart, as seen from the perspective of the bond being broken during the elimination. Without specific details or a diagram, it is not possible to definitively choose between option (a), (b), (c), or (d), as it depends on the actual structure of the substrate molecule in question. The student should look for a projection where the electrophilic carbon-carbon bond is seen head-on and with the leaving group anti to the beta hydrogen.