Final answer:
For the safe administration of theophylline, patients should avoid caffeine-containing products, as the combination can increase the risk of side effects (option c).
Step-by-step explanation:
The instruction a nurse should give to a patient for the safe administration of theophylline is to avoid caffeine-containing products. Theophylline is a medication used to treat respiratory diseases such as asthma and COPD by relaxing the muscles in the lungs and decreasing the response of the airways to irritants.
Since theophylline and caffeine are both stimulants, consuming them together can lead to additive stimulant effects and can cause side effects such as nervousness, irritability, and insomnia. It's also important not to take double doses if one is missed; instead, take the missed dose as soon as possible unless it's almost time for the next dose.
Hence, the answer is option c.