Question

Identify the reagents necessary to accomplish the following steps in the above synthesis of 3-hexanone from acetylene:

a. Organic synthesis
b. Acid-base chemistry
c. Redox reactions
d. Nucleophilic substitution

Answer 1

To accomplish the synthesis of 3-hexanone from acetylene, you would need reagents such as EtMgBr, THF for organic synthesis, TFA/H₂O (1/1) in THF for acid-base chemistry, and 3-tributyltin-2-chloropyridine, Pd(PPh3)4, Cu(I) Br, 1,4-dioxane for nucleophilic substitution.

Step-by-step explanation:

To accomplish the synthesis of 3-hexanone from acetylene, you would need the following reagents:

1. a. Organic synthesis: EtMgBr, THF
2. b. Acid-base chemistry: TFA/H₂O (1/1) in THF
3. c. Redox reactions: No specific reagents mentioned in the provided information
4. d. Nucleophilic substitution: 3-tributyltin-2-chloropyridine, Pd(PPh3)4, Cu(I) Br, 1,4-dioxane