103k views
4 votes
The oriC region of the E. coli chromosome contains three types of DNA sequences: the rich region, box sequence, and the methylation site.

a) True
b) False

User Ronke
by
8.6k points

1 Answer

5 votes

Final answer:

The statement about the oriC region of the E. coli chromosome is false. The oriC region contains A-T rich 13-mer repeats, 9-mer sequences for DnaA binding, and GATC methylation sites, not the described 'rich region,' 'box sequence,' and 'methylation site.' The -10 and -35 regions are consensus sequences in operon promoters, similar across bacterial species.

Step-by-step explanation:

The statement provided in the question regarding the oriC region of the E. coli chromosome is false. The oriC region does contain specific DNA sequences that are crucial for the initiation of DNA replication, but the terms 'rich region', 'box sequence,' and 'methylation site' do not accurately describe these sequences. Instead, oriC consists of several 13-mer repeats that are A-T rich (which contributes to the ease of unwinding the DNA), three 9-mer sequences to which the DnaA initiator proteins bind, and GATC methylation sites that play a role in the regulation of replication initiation.

E. coli DNA is organized into a circular chromosome and contains operons that encode proteins involved in a specific function or biochemical pathway, such as the trp operon for tryptophan biosynthesis or the lac operon for lactose utilization. These operons have promoter regions with recognizable consensus sequences, specifically the -10 and -35 regions. The -10 and -35 regions of prokaryotic promoters are known as consensus sequences because they exhibit a high degree of similarity across bacterial species, facilitating the binding of RNA polymerase and regulatory proteins to initiate transcription.

User Ijas Ahamed N
by
7.5k points