Final answer:
The colonists on the western frontiers responded to the Proclamation of 1763 with dissatisfaction and defiance, disregarding the restrictions it imposed on their ability to settle and purchase land west of the Appalachian Mountains.
Step-by-step explanation:
The colonists on the western frontiers responded to the Proclamation of 1763 with dissatisfaction and defiance. The Proclamation Line, which restricted their ability to settle and purchase land west of the Appalachian Mountains, was seen as an infringement on their rights and aspirations for westward expansion.
The colonists regarded the Proclamation as a form of tyranny and largely ignored it. They continued to move westward, disregarding the British government's efforts to prevent conflict with Native Americans and maintain control over the frontier.
The response of the colonists to the Proclamation of 1763 reflected their growing discontent with British rule and played a role in the increasing tensions that eventually led to the American Revolution.