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Many membrane-damaging toxins lyse red blood cells. These types of toxins, which are often referred to as cause hemolysis that can be observed on blood agar.

a) Antibiotics
b) Neurotransmitters
c) Hemotoxins
d) Antigens

1 Answer

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Final answer:

c) Hemotoxins. The membrane-damaging toxins that cause hemolysis on blood agar are hemotoxins, such as hemolysins produced by bacteria like Streptococcus pyogenes and Clostridium perfringens. These toxins disrupt cell membranes leading to cell lysis, and can cause severe immune reactions with clinical consequences.

Step-by-step explanation:

The types of toxins that often cause hemolysis observed on blood agar are known as hemotoxins. These toxins, including hemolysins and leukocidins, disrupt the membrane function of cells by forming pores or degrading the phospholipid bilayer. For instance, Streptococcus pyogenes produces streptolysins that bind to cholesterol in cell membranes to create pores. Hemolysins like the alpha toxin of Clostridium perfringens and leukocidins such as the toxin produced by Staphylococcus aureus can cause significant damage by destroying cellular integrity, leading to the leakage of cytoplasmic contents and cell lysis. This action is not limited to red blood cells, as originally thought, indicating a broader range of target cells.

Hemotoxins can lead to dangerous clinical outcomes, such as inflammatory responses, hemoglobinuria, and in severe cases, multi-organ failure and death. These toxins highlight the complex interactions between bacterial pathogens and the host's immune system, where the balance of the response can be pivotal to health outcomes.

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