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Which of the following drug profiles is characteristic of current open-angle glaucoma therapy?

a) β-2 agonist
b) α-2 antagonist
c) PGF2a antagonist
d) Rho kinase antagonist

1 Answer

5 votes

Final answer:

The correct drug profile characteristic of current open-angle glaucoma therapy is the Rho kinase antagonist, which works by increasing aqueous humor outflow to lower intraocular pressure.

Step-by-step explanation:

The drug profile characteristic of current open-angle glaucoma therapy is d) Rho kinase antagonist. In current treatment protocols, Rho kinase antagonists are utilized for their ability to reduce intraocular pressure, which is crucial in managing open-angle glaucoma. These drugs act by increasing the outflow of aqueous humor through the trabecular meshwork, thereby reducing intraocular pressure. Both alpha-2 adrenergic receptor agonists and prostaglandin F2α (PGF2α) analogs are also used as glaucoma medications, but they work differently. Alpha-2 agonists decrease aqueous humor production and increase uveoscleral outflow while PGF2α analogs primarily increase uveoscleral outflow.

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