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Is phosphoglyceric acid (BPG) is a byproduct of glycolysis released into the bloodstream when an animal's supply of oxygen is low. Like protons, high BPG decreases hemoglobin's affinity for O_2. The effect of low BPG levels will result in a shift to the blank of the hemoglobin dissociation curve shown.

a) Right
b) Left
c) Center
d) Bottom

1 Answer

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Final answer:

Low levels of 2,3-bisphosphoglycerate (BPG) increase hemoglobin's affinity for oxygen, which results in a leftward shift of the oxygen-hemoglobin dissociation curve. The correct answer is option b) Left.

Step-by-step explanation:

The effect of low levels of 2,3-bisphosphoglycerate (BPG) on the affinity of hemoglobin for oxygen can be explained by the way BPG interacts with hemoglobin. When BPG levels are high, they decrease hemoglobin's affinity for oxygen, promoting the release of oxygen to the tissues. Conversely, when BPG levels are low, the affinity of hemoglobin for oxygen increases, making it hold onto oxygen more tightly. This will result in a shift to the left of the oxygen-hemoglobin dissociation curve. Therefore, the answer to the question is b) Left.

Factors such as increased carbon dioxide levels, higher temperatures, and the presence of byproducts of metabolism like lactic acid can also affect this curve. These factors are known to shift the curve to the right, indicating a lowered affinity for oxygen due to the conditions which encourage the release of oxygen from hemoglobin. This physiological adjustment is crucial for effectively delivering oxygen to where it is needed most during states of increased metabolic demand or low environmental oxygen levels.

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