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DNA-RNA hybrid formation occurs when a single-stranded DNA molecule pairs with a complementary RNA strand. What are the potential consequences of this interaction?

a) Inhibition of protein synthesis.

b) Enhanced gene expression.

c) Increased DNA replication.

d) Formation of a DNA-RNA double helix.

1 Answer

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Final answer:

DNA-RNA hybrid formation can inhibit protein synthesis, potentially influence gene expression, and result in the formation of a DNA-RNA double helix, although it does not directly affect DNA replication.

Step-by-step explanation:

When a single-stranded DNA molecule pairs with a complementary RNA strand, forming a DNA-RNA hybrid, several potential consequences can arise. Firstly, this interaction can lead to an inhibition of protein synthesis, because the formation of a DNA-RNA hybrid can prevent the proper processing and translation of the mRNA molecule. Alternatively, the interaction could influence gene expression by affecting the regulation of certain genes, possibly enhancing or silencing them. Thirdly, increased DNA replication is not typically directly influenced by DNA-RNA hybrid formation.

The pairing between the DNA strand and the RNA strand also results in the formation of a DNA-RNA double helix. This structure is temporary during the process of transcription, where mRNA is synthesized from a DNA template. After transcription, DNA refolds back into its original structure, and the mRNA is processed further before being used in the protein synthesis. RNA-DNA hybrids are also key intermediates during the life cycle of certain viruses, can be involved in gene regulation, and have implications in DNA repair and telomerase activity.

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