Question

In the example with epinephrine, the binding of epinephrine to its receptor leads to the breakdown of cAMP, leading to increased levels of glucose being available to the cell.

a) True
b) False

Answer 1

The statement is false; epinephrine binding to its receptor causes an increase in cAMP, which leads to the conversion of glycogen to glucose, thus making more glucose available to the cell.

Step-by-step explanation:

The statement in the question is false. The binding of epinephrine to its receptor does not lead to the breakdown of cAMP; instead, it leads to an increase in cAMP levels.

epinephrine binds to a G-protein-linked receptor, a series of events is triggered: GTP is exchanged for GDP on the G-protein, which in turn activates adenylyl cyclase. This enzyme then converts ATP to cAMP.

The increase in cAMP activates protein kinase A (PKA), which catalyzes the conversion of glycogen to glucose by activating glycogen phosphorylase kinase (GPK) and in turn glycogen phosphorylase (GP), resulting in increased levels of glucose being available to the cell.