Question

Consider a cell using protein as a primary carbon/energy source. Which of the following amino acids would be most relevant for this cell in terms of glycogen synthesis?

a. Leucine
b. Lysine
c. Serine
d. None of the above

Answer 1

Serine is the correct amino acid relevant for glycogen synthesis as it is glucogenic, allowing it to be used to produce glucose for glycogen accumulation.

Step-by-step explanation:

When considering the synthesis of glycogen from amino acids, we look for amino acids that are glucogenic, meaning they can be converted into intermediates that enter the gluconeogenesis pathway to produce glucose. This glucose can then be polymerized to form glycogen. Among the given options, leucine and lysine are exclusively ketogenic and cannot contribute to gluconeogenesis. However, serine is glucogenic and can contribute to the synthesis of glucose and subsequently glycogen. Thus, serine would be the most relevant amino acid for a cell using protein as a source of carbon/energy for glycogen synthesis.