Question

Which statement about SAGE is true?

A) SAGE is a technique for studying global gene expression based on the premise that a short sequence tag (10-14bp) contains sufficient information to uniquely identify a transcript provided that the tag is obtained from a unique position within each transcript.
B) During SAGE analysis, quantitation of the number of times a particular tag is observed provides the expression level of the corresponding transcript.
C) Colleen was the SAGE queen in her postdoc lab.
D) All of the above

Answer 1

The true statements about SAGE are that it is a global gene expression study technique using sequence tags to identify transcripts and that the quantitation of these tags relates to expression levels of the transcripts.

Step-by-step explanation:

The statement about SAGE (Serial Analysis of Gene Expression) that is true is: A) SAGE is a technique for studying global gene expression based on the premise that a short sequence tag (10-14bp) contains sufficient information to uniquely identify a transcript provided that the tag is obtained from a unique position within each transcript.

B) During SAGE analysis, quantitation of the number of times a particular tag is observed provides the expression level of the corresponding transcript.

The statement C) 'Colleen was the SAGE queen in her postdoc lab.' cannot be verified with the information provided and is likely a non-factual statement or anecdotal at best, hence not part of the correct answer to the question.