Final answer:
The layer of the blood vessel responsible for the issue described is the tunica media.
Step-by-step explanation:
The layer of the blood vessel responsible for the issue described is the tunica media. This layer consists of smooth muscle supported by connective tissue and is primarily responsible for constricting and dilating the blood vessels. In the case of the malady described, the inability of the blood vessels to constrict or dilate properly indicates a dysfunction in the tunica media.