Final answer:
The electrochemical gradient is linked to the electron transport chain through a process called chemiosmosis. The transport of electrons through the respiratory chain pumps protons across the inner mitochondrial membrane, creating a proton gradient. This proton gradient is used by ATP synthase to synthesize ATP from ADP and inorganic phosphate.
Step-by-step explanation:
The electrochemical gradient is linked to the electron transport chain through a process called chemiosmosis. In this process, the exergonic transport of electrons is directly coupled to the endergonic transfer of protons from the intermembrane space to the mitochondrial matrix. The transport of electrons through the respiratory chain pumps protons across the inner mitochondrial membrane, creating a proton gradient. This proton gradient is used by ATP synthase to synthesize ATP from ADP and inorganic phosphate.