Final answer:
Starting in Europe and traveling south, Africa is the first continent you would reach. West Africa was the main region involved in the Trans-Atlantic slave trade. Africa has the highest number of HIV-positive cases. Option A.
Step-by-step explanation:
If you started in Europe and traveled south, the first continent you would reach is Africa. This is due to the geographic location of Europe, which is immediately to the north of the African continent. The two continents are separated by the Mediterranean Sea. When considering the physical area of continents, Africa is the second largest, following Asia.
The region of Africa most directly involved in the Trans-Atlantic slave trade was West Africa. It was the principal source of enslaved Africans who were transported to the Americas. Lastly, it is notable that Africa is also the continent with the overwhelming majority of HIV-positive cases, reflecting significant public health challenges the continent faces. Option A.