Final answer:
The Monroe Doctrine emphasizes isolationism and non-intervention in European affairs by preventing new European colonization in the Americas and avoiding meddling in European internal politics.
Step-by-step explanation:
According to the guidelines in the Monroe Doctrine, the overall message of the political cartoon would most likely convey a sense of isolationism and non-intervention in European affairs. The Monroe Doctrine, established in 1823, primarily sought to prevent new European colonization in the Western Hemisphere and stipulated that the United States would not interfere in the internal affairs of European nations.
The Doctrine also implied a distinction between European and American political systems, advocating that neither should meddle in the other’s affairs. Additionally, President Theodore Roosevelt's Corollary to the Monroe Doctrine, although it pronounced a more assertive American stance, still primarily served to keep European influences out of the Western Hemisphere, particularly in cases of financial instability or political turmoil in Latin American nations, by asserting the United States' right to intervene as an “international police power” to maintain regional stability and fend off European intervention.