Final answer:
The early American practice of slavery conflicted with John Locke's belief in natural rights to life, liberty, and property.
Step-by-step explanation:
John Locke, an influential Enlightenment philosopher, believed that people have fundamental natural rights to life, liberty, and property. These rights are inherent and exist in a state of nature before the creation of any government. A significant practice in early America that conflicted with Locke's beliefs about these natural rights was the slavery of humans. Slavery directly deprived individuals of their natural rights to life, liberty, and property, which Locke considered sacred and inalienable.
According to Locke’s philosophy, a government's primary role is to protect these natural rights, and any form of government that fails to do so, or worse, that deprives people of these rights is unjust and can be overthrown by the people.