Final answer:
True defects in cardiac imaging with CZT detectors should remain consistent when changing from supine to upright imaging, which can help distinguish them from position-related artifacts and improve diagnostic accuracy.
Step-by-step explanation:
When transitioning from supine to upright imaging with Cardiac-specific solid-state camera technology, such as Cadmium Zinc Telluride (CZT) detectors, 'true defects' which are indicative of actual myocardial perfusion abnormalities, should remain consistent regardless of the position. However, in some cases, artifacts caused by attenuation can change with patient positioning. For example, artifacts that might appear in the supine position due to soft tissue attenuation might resolve or change when imaging is done in the upright position, as the positioning can reduce soft tissue attenuation effects. The benefit of upright imaging is that it can help differentiate true defects from attenuation artifacts, thus improving the diagnostic accuracy of myocardial perfusion imaging studies.