Final answer:
Hepatorenal syndrome leads to impaired renal function due to liver failure, typically resulting in increased levels of creatine as a sign of kidney dysfunction.
Step-by-step explanation:
In the context of hepatorenal syndrome, which is a condition where renal perfusion is compromised due to liver failure, levels of creatine are typically increased. This is because hepatorenal syndrome can lead to a type of kidney dysfunction or failure, primarily indicated by an elevated serum creatinine level. Elevated creatinine levels signify a decrease in the kidney's glomerular filtration rate, which is a sign of renal impairment.
The synthesis of certain substances in the liver, such as albumin and coagulation factors, can also be affected, contributing to various hepatic disorders. Creatine levels in the context of liver and kidney interplay can indeed be raised due to the compromised function of the kidneys in filtering waste products from the blood as a consequence of liver damage.