Final answer:
In bronchial asthma, an inflammatory response is caused by cells such as eosinophils, basophils, and mast cells. These cells release inflammatory mediators like histamines and cytokines following allergen exposure, thereby contributing to asthma symptoms and airway inflammation.
Step-by-step explanation:
Cells Contributing to Inflammatory Response in Asthma
The cells that cause a local inflammatory response in bronchial asthma include several types of leukocytes such as eosinophils, basophils, and mast cells. In the case of asthma, when an individual with a sensitized immune system inhales an allergen, an allergic reaction is triggered. Activated Tí2 cells release cytokines interleukin-4 and interleukin-13, which stimulate B cells to produce IgE antibodies. These IgE antibodies bind to mast cells, priming them for a subsequent exposure to the allergen. Upon re-exposure to the allergen, these primed mast cells quickly release inflammatory mediators such as histamines and cytokines, which lead to allergic symptoms and inflammation in the airways. Additionally, eosinophils are recruited and activated, leading to further release of inflammatory substances and sustaining the inflammation. Thus, mast cells and eosinophils play a central role in initiating and perpetuating the inflammatory response in asthma attacks. Basophils can also intensify the response by releasing additional inflammatory mediators.