Final answer:
The best response when assessing a patient over the telephone with a confusing explanation is to politely ask for clarification to ensure understanding, while maintaining a professional and empathetic approach.
Step-by-step explanation:
When assessing a patient over the telephone, and the explanation provided by the patient is unclear, the best response from an ambulatory care nurse would be A. Could you explain that again, I just want to make sure I understand. This response is professional, empathetic, and indicates a willingness to listen, which can help the patient feel more comfortable and may lead to a clearer explanation of their symptoms or situation. Avoidance of terminology that may suggest that the patient's explanation is inadequate, such as in option B, is recommended to maintain a supportive dialogue.