Final answer:
Designating a space for personal mementos in a patient's room is the intervention that directly focuses on emotional well-being during prolonged hospitalization, offering a sense of familiarity and comfort.
Step-by-step explanation:
The intervention specifically focused on helping the patient cope with the emotional responses to prolonged hospitalization is option 4) Designating a corner of the patient's room to display personal mementos. This creates a personal space for the patient, reflecting their identity and history, which can provide comfort and reduce the emotional stress associated with long-term hospital stays. It also supports emotional well-being by making the hospital environment feel more homely and less institutional. The other listed interventions primarily address physical and functional aspects of care rather than emotional support.