Question

Which of the following is probably not a consideration by a medical doctor when prescribing a rectal suppository?

1) To provide a systemic effect
2) Delayed onset of action
3) To provide a local effect
4) To avoid the GI tract

Answer 1

The least likely consideration for a doctor prescribing a rectal suppository is a delayed onset of action because such suppositories are used either for local effects, to bypass the GI tract, or to achieve a systemic effect if well-absorbed rectally.

Step-by-step explanation:

In considering which of the following is probably not a consideration by a medical doctor when prescribing a rectal suppository, the least likely consideration would be a delayed onset of action. This is because rectal suppositories are often used for their ability to bypass the GI tract, which is essential when the oral route is contraindicated due to reasons such as vomiting or the need for intubation. Furthermore, suppositories can indeed be used for their local effect, such as treating conditions of the lower GI tract, and also for achieving a systemic effect if the drug is well-absorbed through the rectal mucosa. Choosing a rectal route of administration is typically to avoid the GI tract when the patient cannot take oral medications or to achieve a therapeutic effect locally.