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What diseases are associated with HLA-DR4

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HLA-DR4 is associated with diseases such as contact dermatitis, multiple sclerosis, and Burkitt Lymphoma. Other diseases include Achondroplasia, Antithrombin deficiency, ADPKD, and BRCA1 and BRCA2 mutations. It's important to note that not all individuals with HLA-DR4 will develop these diseases.

Step-by-step explanation:

HLA-DR4, also known as Human Leukocyte Antigen DR4, is associated with several diseases. Some of the most common diseases associated with HLA-DR4 include contact dermatitis, tuberculin reaction, autoimmune diseases such as diabetes mellitus type I, multiple sclerosis, and rheumatoid arthritis. Other diseases that have been linked to HLA-DR4 include Achondroplasia, Antithrombin deficiency, Autosomal dominant polycystic kidney disease (ADPKD), and BRCA1 and BRCA2 mutations.

In addition, HLA-DR4 has also been associated with Infectious Mononucleosis and Burkitt Lymphoma, which are caused by Human Herpesvirus 4, also known as Epstein-Barr virus (EBV).

It's important to note that while HLA-DR4 may be associated with these diseases, it does not necessarily mean that all individuals with HLA-DR4 will develop these conditions. Genetic and environmental factors also play a role in disease development.

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