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Name the B-cell CD marker: Receptor for EBV?

User Mad Marvin
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Final answer:

The B-cell receptor for EBV is CD21, also known as complement receptor 2 (CR2). B-cells have B-cell receptors (BCRs) consisting of membrane-bound IgD and IgM, which bind specific antigens through unique Fab regions created by genetic rearrangement.

Step-by-step explanation:

The B-cell CD marker that serves as the receptor for Epstein-Barr virus (EBV) is known as CD21, or complement receptor 2 (CR2). EBV specifically targets B cells by binding to this CD21 receptor. The B-cell receptors (BCRs) are membrane-bound molecules on the surface of B cells that principally include membrane-bound IgD and IgM. These BCRs are important for the immune response as they recognize and bind specific antigen epitopes with their Fab antigen-binding regions. B-cell receptors are unique to each B cell due to the genetic rearrangement of V (variable), D (diversity), and J (joining) gene segments, enabling a diverse range of antigen recognition. This diversity allows for the specific binding of antigens, which is critical for the proper activation of B cells and the subsequent immune response.

User Pradeep Banavara
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