Final answer:
Niacin, also known as Vitamin B3, can have several toxicities if consumed in high doses. These include GI upset, flushing, hepatotoxicity, hyperglycemia, and hyperuricemia.
Step-by-step explanation:
Nicotinic acid, also known as niacin or Vitamin B3, can have several toxicities if consumed in high doses:
- GI upset: Taking high doses of niacin can lead to nausea, vomiting, and other gastrointestinal issues.
- Flushing: Niacin can cause flushing of the skin, characterized by redness, warmth, and itching.
- Hepatotoxicity: In some cases, high doses of niacin can lead to liver damage.
- Hyperglycemia: Niacin can cause an increase in blood sugar levels, leading to hyperglycemia.
- Hyperuricemia: High doses of niacin can also increase the levels of uric acid in the blood, which can lead to gout.