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What drugs lower VLDL and L.Lipase activity (lowering triglycerides)?

User Marverix
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Final answer:

Drugs that lower VLDL and triglycerides include fibrates, niacin, omega-3 fatty acids, and statins. Fibrates are particularly effective in decreasing VLDL levels and lipoprotein lipase activity, while statins, known for cholesterol reduction, also aid in lowering triglycerides.

Step-by-step explanation:

The drugs that help in lowering very low-density lipoproteins (VLDL) and consequently reduce triglycerides include fibric acid derivatives (fibrates), niacin, omega-3 fatty acids, and statins. Among these, fibrates such as gemfibrozil and fenofibrate are known for their effectiveness in lowering VLDL levels and lipoprotein lipase activity, which is an enzyme involved in the breakdown of triglycerides.

Statins, which inhibit the enzyme HMG-CoA reductase, are primarily used to lower cholesterol but also have the effect of reducing triglycerides at higher doses. In the presence of high triglyceride levels, especially when lifestyle changes are insufficient, these medications can be prescribed by healthcare providers. It is vital to monitor the lipid profile regularly when undergoing treatment with these medications to ensure effectiveness and manage any potential side effects.

User Crowhill
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3 votes

Final answer:

Drugs that lower VLDL and triglycerides include fibrates, niacin, omega-3 fatty acids, and statins. Fibrates are particularly effective in decreasing VLDL levels and lipoprotein lipase activity, while statins, known for cholesterol reduction, also aid in lowering triglycerides.

Step-by-step explanation:

The drugs that help in lowering very low-density lipoproteins (VLDL) and consequently reduce triglycerides include fibric acid derivatives (fibrates), niacin, omega-3 fatty acids, and statins. Among these, fibrates such as gemfibrozil and fenofibrate are known for their effectiveness in lowering VLDL levels and lipoprotein lipase activity, which is an enzyme involved in the breakdown of triglycerides.

Statins, which inhibit the enzyme HMG-CoA reductase, are primarily used to lower cholesterol but also have the effect of reducing triglycerides at higher doses. In the presence of high triglyceride levels, especially when lifestyle changes are insufficient, these medications can be prescribed by healthcare providers. It is vital to monitor the lipid profile regularly when undergoing treatment with these medications to ensure effectiveness and manage any potential side effects.

User James Fassett
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