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Which laboratory test result most accurately reflects a patient's nutritional status?

1) Albumin
2) Prealbumin
3) Transferrin
4) Hemoglobin

User Consprice
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1 Answer

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Final answer:

Prealbumin is the most accurate laboratory test result for reflecting a patient's nutritional status as it is a sensitive biomarker that responds to nutritional changes rapidly compared to albumin, hemoglobin, and transferrin.

Step-by-step explanation:

Among the given options, prealbumin most accurately reflects a patient's nutritional status. Prealbumin is a transport protein in the blood that has a shorter half-life compared to albumin, making it a more sensitive biomarker for nutritional assessment. It responds to nutritional changes within 2-3 days, whereas albumin reacts in weeks. Therefore, a prealbumin test is often used by healthcare providers to evaluate the effectiveness of nutrition intervention more promptly.

Although albumin is the most abundant protein in human blood plasma and is a reflection of the body's protein reserves over the long term, it has a half-life of approximately 20 days, which makes it less sensitive to recent changes in a patient's nutritional status. Hemoglobin levels can be affected by factors other than nutrition, such as blood loss or disorders like anemia. Transferrin, another protein synthesized in the liver, is a marker of iron metabolism and not directly indicative of overall nutritional status.

User Johncosta
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