Final answer:
A dental assistant is permitted to perform pit and fissure sealants under specific conditions such as completing a proper sealant application course and working under dentist supervision.
Step-by-step explanation:
A dental assistant may perform pit and fissure sealants only under the supervision of a dentist and only if they have completed a sealant application course. Prior experience in performing pit and fissure sealants can be beneficial, but it is the formal education and training that are essential, accompanied by supervision, to ensure patient safety and adherence to dental practice regulations.