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If a patient with thyroid ophthalmopathy presents a few months later with severe proptosis (>28mm), reduced vision in the left eye, colo desaturation, RAPD, and central scotoma on visual field testing, what is the most likely cause?

1) Papilledema
2) Retinal detachment
3) Optic neuritis
4) Graves' ophthalmopathy

User Cavan
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1 Answer

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Final answer:

The symptoms described are most indicative of Graves' ophthalmopathy, a severe eye condition associated with Graves' disease. It causes inflammation and swelling within the orbit leading to optic nerve compression, resulting in symptoms such as proptosis, reduced vision, and central scotoma. Option C.

Step-by-step explanation:

If a patient with thyroid ophthalmopathy presents with severe proptosis (greater than 28mm), reduced vision, color desaturation, Relative Afferent Pupillary Defect (RAPD), and central scotoma on visual field testing, the most likely cause of these symptoms is Graves' ophthalmopathy. Graves' ophthalmopathy, a hallmark sign of Graves' disease, is associated with hyperthyroidism and can lead to severe eye symptoms, including inflammation and swelling within the orbit, which can compress the optic nerve. This can lead to optic nerve dysfunction, as evidenced by symptoms such as reduced vision, color desaturation, an RAPD, and central scotoma.

When evaluating visual field deficits such as the central scotoma, it's important to distinguish from conditions like bilateral hemianopia that suggest damage to the optic chiasm which could be caused by a pituitary tumor. Swelling around the optic nerve can also occur in conditions like meningitis, emphasizing the importance of understanding the underlying cause of optic nerve dysfunction.

Proptosis, or protruding eyes, and lid retraction are indicative signs of hyperthyroidism or Graves' disease. Hormonal imbalances caused by thyroid conditions can be treated with medications to reestablish balance.

User Erbal
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