Question

Loss of corneal sensation is seen in?

1) Corneal infection
2) Corneal ulcer
3) Corneal herpes
4) Corneal neuropathy

Answer 1

Loss of corneal sensation is primarily observed in conditions like herpes keratitis and corneal neuropathy, (option 4) which are associated with infections like HSV-1 and underlying nerve damage.

Step-by-step explanation:

Loss of corneal sensation can be seen in various conditions affecting the eye. Notable amongst these conditions is herpes keratitis, which is an infection of the cornea caused by the herpes simplex virus (HSV-1). This can lead to symptoms such as irritation, excess tears, and sensitivity to light. Additionally, corneal neuropathy can result in reduced corneal sensation. Such neuropathy can be a consequence of various etiologies, including diabetes or surgical procedures on the eye.

While corneal infections and corneal ulcers can also impair sensation, these are generally associated more with pain due to inflammation rather than a loss of sensation. Conditions such as Acanthamoeba keratitis result in inflammation and can lead to severe damage to the cornea, potentially causing vision impairment or blindness. However, the direct loss of sensation would not typically be the primary symptom in these cases.