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A client with atrial fibrillation is receiving a continuous heparin infusion at 1000 units/hr. The nurse would determine that the client is receiving the therapeutic effect based on which of the following results?

A. Prothrombin Time of 12.5 seconds
B. Activated partial thromboplastin time of 60 seconds
C. Activated Partial thromboplastin time of 28 seconds
D. Activated Partial thromboplastin time longer than 120 seconds

1 Answer

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Final answer:

The therapeutic effect of heparin in a client with atrial fibrillation is indicated by an Activated Partial Thromboplastin Time (aPTT) of 60 seconds, which is within the therapeutic range of 1.5 to 2.5 times the normal value.

Step-by-step explanation:

A client with atrial fibrillation on a continuous heparin infusion would have their therapeutic response measured by the Activated Partial Thromboplastin Time (aPTT). The normal aPTT range is about 30 to 40 seconds, and when on heparin therapy, the therapeutic range is typically 1.5 to 2.5 times the normal value. Therefore, an aPTT of 60 seconds would indicate a therapeutic level of anticoagulation in this case. Prothrombin Time (PT) is not the correct measure for heparin therapy, and an aPTT significantly longer than the treatment range could suggest an excessive anticoagulant effect, risking bleeding complications.

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