Question

a nurse is preparing to administer indomethacin to a client. which laboratory tests will the nurse prioritize in the preadministration assessment? select all that apply.

Answer 1

In the preadministration assessment before administering indomethacin, the nurse will prioritize the following laboratory tests: renal function tests, complete blood count (CBC), and liver function tests.

Step-by-step explanation:

1. **Renal Function Tests:**

Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID), can impact renal function. The nurse will prioritize tests such as serum creatinine and blood urea nitrogen (BUN) to assess baseline renal function. Monitoring renal function is crucial to identify any signs of nephrotoxicity or impaired renal function that may arise as a side effect of indomethacin.

2. **Complete Blood Count (CBC):**

Indomethacin can affect blood components, and the nurse will prioritize CBC to assess for any potential alterations in blood cell counts. Specifically, the nurse will be attentive to changes in hemoglobin, hematocrit, and platelet levels. Anemia or thrombocytopenia are potential adverse effects that need close monitoring.

3. **Liver Function Tests:**

Liver function tests, including alanine aminotransferase (ALT) and aspartate aminotransferase (AST), are essential to evaluate the impact of indomethacin on hepatic function. Elevations in these enzymes could indicate hepatotoxicity, and monitoring liver function is crucial for the early detection of any adverse effects on the liver.

Performing these laboratory tests before indomethacin administration provides a baseline for comparison during and after treatment. It enables the nurse to detect and manage any potential adverse effects promptly. Close monitoring of these parameters contributes to the overall safety and well-being of the client receiving indomethacin therapy.