Final answer:
Pontiac's Rebellion was the uprising in the Great Lakes area after the French and Indian War. Led by Pontiac, it involved various Native American tribes attacking British forts and settlers, which resulted in the British imposing the Proclamation of 1763 to try and prevent further conflict.
Step-by-step explanation:
The uprising in the Great Lakes area following the end of the French and Indian War is known as Pontiac's Rebellion. After the British took control of the French territories in the region, Pontiac, leader of the Ottawa, foresaw the threat of British expansion into Native American lands.
Pontiac encouraged a confederation of different tribes, including the Shawnee, Munsee, Wyandot, Seneca, Delaware, Huron, Potawatomi, Ojibwa, and Ottawa, to join in an alliance against the British settlers and forces. Consequently, in May of 1763, these tribes initiated attacks on British forts and settlements, such as the siege of Fort Detroit, leading to significant violence and casualties.
The rebellion highlighted the Native Americans' dependency on French trade and the precarious British control over the Ohio Valley. As a response to Pontiac's War, the British enacted the Proclamation of 1763, attempting to stabilize the region by limiting colonial expansion and designating lands west of the Appalachian Mountains for Native Americans. Despite the effort, it was clear that racial tensions and the struggle for control over the territory would persist.