Final answer:
Rouen is a significant industrial and agricultural hub in France, strategically positioned along the Seine River that facilitates commerce to and from Paris.
Step-by-step explanation:
Rouen is an industrial and agricultural hub located in France and second-largest in importance after the capital, Paris. This city is critical for commerce that travels to and from Paris along the Seine River. While the provided reference mentions the Rhine River, which is vital for Central European commerce, it is the Seine that is relevant for Rouen. This river supports a variety of transportation, including barges, which are a common sight along French waterways. Addressing a common confusion, it's important to note that the Rhine is not the river flowing through Rouen. The city's economy benefits from the River Seine, which is navigable and plays a central role in the movement of agricultural and industrial products.