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What do lysosomes contain? What is their function? Where are they active? Which enzymes are involved?

User Maud
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Final answer:

Lysosomes are organelles that contain digestive enzymes and function to break down cellular debris, non-functioning organelles, and pathogens. They maintain an acidic environment for optimal enzyme activation and are involved in processes like autophagy and apoptosis. Lysosomes are especially prominent in immune cells such as macrophages for destroying bacteria and other pathogens.

Step-by-step explanation:

Lysosomes are membrane-bound organelles found in eukaryotic cells that contain a number of powerful digestive enzymes, such as lipases, proteases, and nucleases. These enzymes are responsible for breaking down various organic polymers, including old proteins, foreign materials, and cellular waste.

Lysosomes operate by maintaining an acidic internal environment, optimal for enzyme activation, which is achieved through proton pumps in their membranes.

The primary functions of lysosomes include breaking down non-functioning organelles and macromolecules, as well as destroying pathogens that enter the cell through the process of phagocytosis.

In white blood cells like macrophages, lysosomes are crucial for digesting engulfed bacteria and other pathogens. One significant and controlled process mediated by lysosomes is autophagy, where the lysosome digests the cell's own components, playing a role in cell maintenance. Under certain circumstances, lysosomes can induce apoptosis by releasing their enzymes into the cytoplasm of the cell, leading to cell death.

Lysosomes are active throughout the cell, especially in phagocytic cells of the immune system. The enzymes they contain, acid hydrolases, become active in the acidic environment inside the lysosome, ensuring the protection of the rest of the cell from these potentially damaging enzymes.

User Sid Shukla
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