Final Answer:
Sickle cell anemia is a consequence of a point mutation in the Beta-globin gene.
Step-by-step explanation:
The specific point mutation in the Beta-globin gene associated with sickle cell anemia results in the substitution of a single amino acid in the hemoglobin protein. This mutation causes the formation of abnormal hemoglobin, known as hemoglobin S. Under certain conditions, hemoglobin S molecules polymerize, leading to the characteristic sickle shape of red blood cells.
The altered shape reduces the flexibility of the red blood cells, causing them to clump together and obstruct blood vessels. This obstruction leads to various complications, including pain, organ damage, and an increased risk of infections. Sickle cell anemia is an inherited genetic disorder, with individuals inheriting the mutated gene from both parents.