Final answer:
The subject pertains to the conversion of glutamate to glutamine in the presence of ATP hydrolysis, a fundamental biological process in amino acid biosynthesis.
Step-by-step explanation:
The conversion of glutamate (Glu) to glutamine (Gln), which involves ATP hydrolysis, is a key metabolic process in the biosynthesis of amino acids. In this reaction, an ATP molecule is hydrolyzed, providing the energy necessary for the addition of an ammonia group to glutamate, thus forming glutamine.
This is an important step as it facilitates the incorporation of ammonium ion (NH4+), which can then be safely transported and used in the synthesis of other amino acids through transamination reactions.
Glutamate dehydrogenase is an enzyme that catalyzes the reversible oxidative deamination of glutamate, forming α-keto glutarate and ammonia. In the reverse reaction, the enzyme uses NADPH as a reducing agent to convert α-keto glutarate into glutamate, which can subsequently be converted into glutamine. This illustrates the intricate interplay between metabolic pathways in the synthesis and utilization of amino acids.
The question is incomplete, The complete question is given below:
Explore the process of the conversion of Glutamate (Glu) to Glutamine (Gln) facilitated by coping with ATP hydrolysis